One-Trial Interhemispheric Transfer of a Learning Engram

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Science  07 Apr 1961:
Vol. 133, Issue 3458, pp. 1077-1078
DOI: 10.1126/science.133.3458.1077


By using spreading depression to decorticate temporarily one hemisphere in rats, a learning trace was established in the opposite functional hemisphere. Spontaneous transfer of the engram from the trained hemisphere to the untrained hemisphere does not occur when both hemispheres are functional. If, however, the animal was allowed to make one reinforced response, complete transfer of the engram to the untrained hemisphere occurred.