Recovery from Electroconvulsive Shock as a Function of Infantile Stimulation

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Science  05 May 1961:
Vol. 133, Issue 3462, pp. 1428
DOI: 10.1126/science.133.3462.1428


Eighty Wistar rats were handled at 2 to 5, 6 to 9, or 10 to 13 days of age, or not at all. In adulthood each group was split into halves with one-half of each group receiving electroconvulsive shock treatment. Assays of sugar concentration in the blood serum 24 hours after the convulsions indicated that subjects handled at 2 to 5 days of life exhibited no effect of the treatment, whereas all other groups showed marked increases in blood sugar concentration.