Patterns of Corticosteroid and Pepsinogen Change Related to Emotional Stress in the Monkey

Science  19 May 1961:
Vol. 133, Issue 3464, pp. 1596-1598
DOI: 10.1126/science.133.3464.1596


In association with conditioned avoidance sessions of 72 hours' duration, monkeys showed a response pattern characterized by increased levels of 17-hydroxy-corticosteroids and decreased levels of pepsinogen during the stress period, with a marked and prolonged elevation of pepsinogen levels occurring during the recovery period.