Radioprotective Activity of a Phenanthrene Derivative in Mice

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Science  14 Jul 1961:
Vol. 134, Issue 3472, pp. 111
DOI: 10.1126/science.134.3472.111


2-Acetyl-7-oxo-1,2,3,4,4a,4b,5,6,7,9,10,lOa-dodecahydrophenanthrene possessed radioprotective activity when injected subcutaneously (in sesame oil) into 20-day-old male Swiss mice once daily for the 10 days prior to irradiation by cobalt-60 at 30 days of age. Female mice similarly treated were not protected.