Deamination of Adenine by Ionizing Radiation

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Science  14 Jul 1961:
Vol. 134, Issue 3472, pp. 113
DOI: 10.1126/science.134.3472.113


A small amount of hypoxanthine is formed when a solution of adenine is irradiated. This has been detected by using C14-labeled adenine and the techniques of paper chromatography and liquid-scintillation counting. The biological significance of this conversion is suggested.