A New Thiamine Derivative, S-Benzoylthiamine O-Monophosphate

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Science  21 Jul 1961:
Vol. 134, Issue 3473, pp. 195-196
DOI: 10.1126/science.134.3473.195


S-Benzoylthiamine O-monophosphate has been synthesized, and its physicochemical and biological properties have been investigated. It is a stable crystalline substance, it exerts thiamine activity approximately equivalent to that of thiamine hydrochloride in thiamine-requiring microorganisms, and it is easily absorbed in organisms, particularly by oral administration.