Arginine and Pyrimidine Biogenesis in Neurospora

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Science  18 Aug 1961:
Vol. 134, Issue 3477, pp. 471-472
DOI: 10.1126/science.134.3477.471


The growth-promoting activity of propionic acid and related compounds for the pyrimidine-less strain, Neurospora crassa 1298, is markedly inhibited by arginine. The data suggest that arginine exerts an inhibitory effect upon or represses the synthesis of an enzyme involved in pyrimidine formation.