Antigen Disappearance in Hibernating Ground Squirrels

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Science  15 Sep 1961:
Vol. 134, Issue 3481, pp. 734-735
DOI: 10.1126/science.134.3481.734


The rate of antigen disappearance was studied in hibernating ground squirrels (Citellus tridecemlineatus) injected with I131-labeled bovine serum albumin. There was no detectable disappearance of antigen during 14 days of hibernation. The induction period, however, ended 5 days after arousal as compared to a 7-day induction period in nonhibernating ground squirrels.