Effects of Phenylalanine Diet on Brain Serotonin in the Rat

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Science  22 Sep 1961:
Vol. 134, Issue 3482, pp. 831-832
DOI: 10.1126/science.134.3482.831


Hooded rats fed diets rich in phenylalanine showed poorer performance on the Hebb-Williams maze than controls, as well as decreased brain serotonin levels. There did not appear to be a causal relationship between these findings, and the findings do not appear to be attributable either to a generalized behavioral defect or to inadequate dietary intake.