Localized Cooling in the Brain

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Science  10 Nov 1961:
Vol. 134, Issue 3489, pp. 1520-1521
DOI: 10.1126/science.134.3489.1520


A slender refrigeration probe for the production of reversible discrete lesions within the central nervous system of man and experimental animals is described. Cooling, in the region of the third nerve nucleus in cats, produced pupillary dilatation which was quickly reversed when the temperature around the third nerve nucleus returned to normal.