Accumulation of Potassium Anaerobically by Renal Medullary Slices

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Science  17 Nov 1961:
Vol. 134, Issue 3490, pp. 1622-1623
DOI: 10.1126/science.134.3490.1622


Potassium accumulation occurred in leached slices of the inner medulla of the dog kidney incubated under anaerobic conditions at 37°C with glucose as substrate, but was blocked by inhibitors of glycolysis. Aerobically, only slight accumulation occurred with succinate as substrate at 37°C, and this was blocked by dinitrophenol. These findings were in contrast to those obtained with kidney cortex slices under the same conditions.