Reports

Presence of Toxic Factors in Urine from Schizophrenic Subjects

Science  24 Nov 1961:
Vol. 134, Issue 3491, pp. 1687-1688
DOI: 10.1126/science.134.3491.1687

Abstract

Mice injected intraventricularly with toxic substances extracted from urine exhibited differential behavioral changes of novel character. Extracts from schizophrenics showed significantly more toxicity than those from nonschizophrenics. Further purification by a chromatographic procedure indicated that at least two currently unidentified active components are present.

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