Disinhibition of Inhibitory Conditioned Responses following Selective Brain Lesions in Dogs

Science  22 Dec 1961:
Vol. 134, Issue 3495, pp. 2040-2041
DOI: 10.1126/science.134.3495.2040


Discrete lesion of the genual portion of the anterior cingulate gyrus in three dogs produced temporary disinhibition of preoperatively trained inhibitory food conditioned responses. This disinhibition was accompanied by increase in general behavior motivated by food reinforcement. Lesion of the posterior cingulate gyrus in three other dogs did not produce such impairment.