Toxohormone-like Factor from Microorganisms with Impaired Respiration

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Science  22 Dec 1961:
Vol. 134, Issue 3495, pp. 2041-2042
DOI: 10.1126/science.134.3495.2041


A substance that significantly depresses liver catalase values when injected into mice has been isolated from biochemical mutants of yeasts and staphylococci with impaired respiration. This is considered as an important argument in support of the Warburg hypothesis on the origin of cancer cells.