Metabolism of Glycogen in Skin and the Effect of Radiation

Science  19 Jan 1962:
Vol. 135, Issue 3499, pp. 216-217
DOI: 10.1126/science.135.3499.216


Continuous biosynthesis of glycogen was demonstrated by perfusion of the skin of dogs with uniformly labeled C14-glucose. If the skin is irradiated in vivo with an erythemal dose of x-rays 24 hours prior to perfusion, the uptake of radioactive glucose into glycogen is significantly increased. The irradiation effect appears to be due to enzymatic dysbalance.