Taste-Structure Correlation with α-D-Mannose and β-D-Mannose

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Science  02 Feb 1962:
Vol. 135, Issue 3501, pp. 367-368
DOI: 10.1126/science.135.3501.367


The so-called ambiguity of taste perception of D-mannose has been traced to actual differences in taste between the two anomers of this substance. Preliminary data indicate strongly that the α-anomer is sweet (sucrose-like) and the β-anomer is bitter (quinine-like). The difference in taste is attributed to the slight difference in structures of the anomers.