Histochemical Distribution of Acid Phosphatase in Healing Wounds

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Science  23 Feb 1962:
Vol. 135, Issue 3504, pp. 672
DOI: 10.1126/science.135.3504.672


When wounds are inflicted in the palate, tongue and skin of Wistar rats and guinea pigs, acid phospatase activity in proliferating epithelium of these wounds is markedly decreased from that in normal epithelium; the enzyme reappears as soon as keratinization is evident. In connective tissue the enzyme is found especially in foreign body giant cells and in histiocytes in macrophagic function.