Chlorpromazine Affects Permeability of Resting Cells of Tetrahymena pyriformis

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Science  09 Mar 1962:
Vol. 135, Issue 3506, pp. 793-794
DOI: 10.1126/science.135.3506.793


Incubation of cell suspensions of Tetrahymena pyriformis with chlorpromazine increased the permeability of the cell membrane. This permeability change could be measured either biochemically by the increased entrance of a chelator or physically by change in light scattering.