Estrogen-Sensitive Neurons and Sexual Behavior in Female Cats

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Science  27 Apr 1962:
Vol. 136, Issue 3513, pp. 322-323
DOI: 10.1126/science.136.3513.322


The stimulation of mating behavior by means of the stereotaxic introduction of small implants of solid C14-diethylstilbestrol di-n-butyrate to the hypothalamus of ovariectomized cats is described. Autoradiographic examination of the brains of mating animals reveals that certain neurons in the region of these implants show a selective affinity for labeled estrogen.