Immunological Competence of Placenta

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Science  04 May 1962:
Vol. 136, Issue 3514, pp. 382-383
DOI: 10.1126/science.136.3514.382


The presence of immunologically competent cells in placenta has been investigated by use of the experimental model of runt disease in inbred strains of mice. The injection of placental cells from C57/B1 mice into newborn Balb/C mice resulted in death in the 2nd to 4th week. Evidence is presented that death was caused by immunologically competent fetal cells.