Arrangement of DNA in Living Sperm: A Biophysical Analysis

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Science  29 Jun 1962:
Vol. 136, Issue 3522, pp. 1122-1124
DOI: 10.1126/science.136.3522.1122-a


The submicroscopic arrangement of DNA molecules in living sperm is analyzed by new, highly sensitive polarization optical techniques. It is concluded that the molecules are arranged as a coil of a coil in sperm chromosomes, which in turn appear to be arranged in single file with a definite sequence.