Mechanism of Tissue Reconstruction by Dissociated Cells, II: Time-Course of Events

Science  07 Sep 1962:
Vol. 137, Issue 3532, pp. 762-763
DOI: 10.1126/science.137.3532.762


The details of the process by which cells sort out and reconstruct tissues within aggregates containing two kinds of tissue cells have been correctly predicted from considerations of the kinetic and adhesive properties of such cells. The requisite properties are discreteness, motility, and differential mutual adhesiveness among the types of cells present.