Ribonucleic Acid in "Transformation" of Lymphoid Cells

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Science  21 Sep 1962:
Vol. 137, Issue 3534, pp. 976-977
DOI: 10.1126/science.137.3534.976


When incubated with "reactive" ribonucleic acid extracted from lymph nodes of rabbits immunized by skin homografts, "neutral" lymph node cells from nongrafted rabbits were apparently altered to a state of transpiantation immunity, as manifested by a positive skin reaction upon injection of these cells into the donor of the skin homografts.