Conditioning of Extrasystoles in Humans with Respiratory Maneuvers as Unconditional Stimulus

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Science  28 Sep 1962:
Vol. 137, Issue 3535, pp. 1060-1061
DOI: 10.1126/science.137.3535.1060


Extrasystoles are known to occur in some healthy individuals during common respiratory maneuvers such as holding the breath. Evidence is presented which shows that under controlled laboratory conditions this kind of extrasystole can be conditioned. Conditional stimuli signaling inspiration and expiration acquired the properties of the respiratory maneuvers by inducing extrasystoles during normal breathing.