Serial Propagation of Influenza B (Lee) Virus in a Transmissible Line of Canine Kidney Cells

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Science  05 Oct 1962:
Vol. 138, Issue 3536, pp. 42-43
DOI: 10.1126/science.138.3536.42


The serial propagation of influenza B (Lee) virus has been demonstrated in a transmissible line of canine kidney cells, as evidenced by the presence of cytopathic effects and hemagglutinins in each of six consecutive tissue-culture passages, and by egg infectivity titers of 10-4.3 and 10-4.1 per 0.1 ml in 3rd and 5th tissue culture fluids, respectively.