Virus Neutralization Test in a Capillary Tube

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Science  19 Oct 1962:
Vol. 138, Issue 3538, pp. 448
DOI: 10.1126/science.138.3538.448


A simple and accurate virus titration method which requires extremely low numbers of cells per test vessel is described. Inhibition of metabolism was the criterion for 50 percent end point analysis when capillary tubing was used as the cell culture container. Virus neutralization titers were obtained within 24 hours.