Ribonucleotides of RNA: Separation by Chromatography on Sheets of Diethylaminoethylcellulose

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Science  26 Oct 1962:
Vol. 138, Issue 3539, pp. 515-516
DOI: 10.1126/science.138.3539.515


The four main ribonucleotides of RNA can be separated on diethylaminoethylcellulose paper sheets, with results comparable to column chromatography, by irrigation with 0.05M formic acid for 2 to 3 hours, and then reversing the direction of irrigation with 4M formic acid.