Acid Phosphatase in Serum: Increase in Acute Myocardial Infarction

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Science  04 Jan 1963:
Vol. 139, Issue 3549, pp. 51-52
DOI: 10.1126/science.139.3549.51


Ten consecutive cases of acute transmural myocardial infarction were accompanied by a rise of 50 to 400 percent in the serum acid phenylphosphatase. The increase in phosphatase began several hours after onset of symptoms and lasted 3 to 5 days. A similar rise was seen during the acute stages of other thromboembolic diseases. While the mechanism by which this acid hyperphenylphosphatasia occurs is not clear, platelets may play an important role.