Tissue Levels of Norepinephrine and Epinephrine in Hemorrhagic Shock

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Science  04 Jan 1963:
Vol. 139, Issue 3549, pp. 54
DOI: 10.1126/science.139.3549.54


Severe depletion of endogenous norepinephrine was observed in the brain, heart, liver, and spleen of albino rabbits in which hemorrhagic shock had been induced. On the other hand, the epinephrine content of these tissues was significantly elevated above the levels in tissues of control animals. The norepinephrine and epinephrine levels of skeletal muscle in shocked animals remained unaffected.