Malaria Parasites: Fluorescent Antibody Technique for Tissue Stage Study

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Science  01 Feb 1963:
Vol. 139, Issue 3553, pp. 405-406
DOI: 10.1126/science.139.3553.405


Tissue stages of avian and simian malarias were stained by the fluorescent antibody method. The fluorescent bodies proved to be parasites in tests for immunological specificity and on restaining with Giemsa. These results suggest a method for studying two important aspects of mammalian malarias—namely, the cycle in the mammalian host and the immunological relationships among malarias indicated by tissue stages.