Lactate Dehydrogenases in Human Testes

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Science  15 Feb 1963:
Vol. 139, Issue 3555, pp. 601-602
DOI: 10.1126/science.139.3555.601


A unique form of lactate dehydrogenase was observed in the starch-gel electrophoretic patterns of adult human testes. It was present in sperm, but absent in prepubertal testes. Its electrophoretic mobility, heat stability, kinetic behavior with pyridine nucleotide analogs, and chromatographic characteristics on diethylaminoethyl cellulose were intermediate to those observed for lactate dehydrogenase isozymes 3 and 4.