Intrauterine Foreign Body: Effect on Pregnancy in the Rat

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Science  01 Mar 1963:
Vol. 139, Issue 3557, pp. 833-834
DOI: 10.1126/science.139.3557.833


A silk suture placed in the lumen of one uterine horn of rats before mating prevented pregnancy in that horn although normal implantation occurred in the unoperated horn. The suture did not interfere with fertilization or the tubal transport of ova, nor did it induce a decidual reaction; it appeared to prevent pregnancy by causing failure of implantation.