Deoxyribonuclease Sensitivity of Ribonucleic Acid Synthesizing System from Tobacco Leaves

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Science  08 Mar 1963:
Vol. 139, Issue 3558, pp. 924-925
DOI: 10.1126/science.139.3558.924


A fraction from tobacco leaf cells, containing nuclei and capable of synthesizing ribonucleic acid in the presence of the four ribonucleoside triphosphates, was inactive after incubation with deoxyribonuclease, suggesting that deoxyribonucleic acid plays an essential role in the reaction. Almost complete inhibition was obtained even with concentrations of deoxyribonuclease which removed less than half the original acid-insoluble deoxyribonucleic acid.