Chelation of Calcium by Lactose: Its Role in Transport Mechanisms

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Science  22 Mar 1963:
Vol. 139, Issue 3560, pp. 1205-1206
DOI: 10.1126/science.139.3560.1205


Lactose, like other sugars and polyols, prevents or delays the precipitation of calcium ion in the presence of bicarbonate buffer. That an uncharged calcium-lactose complex is formed was demonstrated by the use of paper electrophoresis and of calcium-45 as a label for the complex. Enhancement of the intestinal absorption of calcium ion by sugars could result from a complex of low molecular weight.