Loss of Radioactivity from Labeled DNA of Primary Human Amnion Cells

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Science  22 Mar 1963:
Vol. 139, Issue 3560, pp. 1211-1212
DOI: 10.1126/science.139.3560.1211


Primary human amnion cultures labeled with glycine-2-C14 or thymidine-2-C14 released more radioactivity into the media than could be accounted for by cell replacement. This is interpreted as degradation of acid-insoluble polydeoxynucleotides in a living human cell.