Electrocardiographic Notching in Rats Deficient in Essential Fatty Acids

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Science  22 Mar 1963:
Vol. 139, Issue 3560, pp. 1213
DOI: 10.1126/science.139.3560.1213


A notch has been seen in the electrocardiograms of rats who were fed diets deficient in essential fatty acids. This notching occurs consistently at a point 37 percent through the QRS-complex. It can be prevented by the addition of small amounts of linoleate, linolenate, or arachidonate to the diet of these rats.