Antigenic Material: Persistence in Hypersensitive Cells

See allHide authors and affiliations

Science  05 Apr 1963:
Vol. 140, Issue 3562, pp. 71-72
DOI: 10.1126/science.140.3562.71


Radioactivity derived from injections of tritiated tetanus toxin was observed in lymphocytes and macrophages for as long as 9 months after injection into immunized mice. These labeled cells became highly vacuolated and attracted eosinophils and lymphocytes when the animals were reinjected with specific antigen.