l-α-Tocopheryl Acetate: Biological Activity

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Science  05 Apr 1963:
Vol. 140, Issue 3562, pp. 80
DOI: 10.1126/science.140.3562.80


l-α-Tocopheryl acetate has 42 percent of the activity of d-α-tocopheryl acetate when compared in the rat hemolysis test. Based on this activity a potency ratio of 1.4 : 1.0 for d-α-tocopheryl acetate compared to dl-α-tocopheryl acetate was established; this confirms the currently accepted biological ratio. Preparations of dl-α-tocopheryl acetate from phytol and from isophytol were equally active in the rat hemolysis test.