Tarichatoxin: Isolation and Purification

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Science  19 Apr 1963:
Vol. 140, Issue 3564, pp. 295-296
DOI: 10.1126/science.140.3564.295


The potent neurotoxin occurring in the embryos of the California newt, Taricha torosa, has been obtained in crystalline form. With a lethal subcutaneous dose of approximately 0.14 micrograms for a 20-gram mouse, it is, along with saxitoxin and tetrodotoxin, one of the most toxic nonprotein substances known.