Histone and DNA in Isolated Nuclei from Chicken Brain, Liver, and Erythrocytes

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Science  19 Apr 1963:
Vol. 140, Issue 3564, pp. 316-318
DOI: 10.1126/science.140.3564.316


In isolated brain and liver nuclei the ratio of histone to deoxyribonucleic acid is lower than in nuclei from erthrocytes. Deoxyribonucleoproteins from brain and liver, in contrast to deoxyribonucleoproteins from erythrocytes, are more soluble in isotonic sodium chloride.