Reports

Intracranial Self-Stimulation in Man

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Science  26 Apr 1963:
Vol. 140, Issue 3565, pp. 394-396
DOI: 10.1126/science.140.3565.394

Abstract

Intracranial self-stimulation techniques, modified for use with neuropsychiatric patients, provide data suggestive of positive and negative reinforcing properties of brief electrical stimulation to various subcortical structures of the human brain.