Strychnine: Its Action on Spinal Motoneurons of Cats

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Science  17 May 1963:
Vol. 140, Issue 3568, pp. 806-808
DOI: 10.1126/science.140.3568.806


In cats strychnine does not alter measurably the potential, threshold, after potentials, or refractoriness of the membrane of the spinal motoneurons. Increased reflexes probably result from increase of excitatory impingement upon motoneurons. Spikes recorded during a rapid succession of nerve impulses produced by strychnine ("strychnine burst") suggest that soma membrane resistance is appreciable during stimulation.