Burns and Other Skin Lesions: Microcirculatory Responses in Man during Healing

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Science  31 May 1963:
Vol. 140, Issue 3570, pp. 994-996
DOI: 10.1126/science.140.3570.994


Morphological changes in the cutaneous microcirculation during wound healing have been studied by capillaroscopy in man. In experimental and accidental burns, abrasions, and lacerations, in addition to the anticipated revascularization by the deeper dermal vessels, a distinctive pattern of response by the surrounding papillary capillaries was consistently observed. This appears to be a general phenomenon in healing of skin lesions and suggests the possibility that a potent capillary-attracting factor may be produced within the injured tissue.