Cancer: Relation of Prenatal Radiation to Development of the Disease in Childhood

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Science  07 Jun 1963:
Vol. 140, Issue 3571, pp. 1102-1104
DOI: 10.1126/science.140.3571.1102


Experimental evidence indicating a linear response and the absence of a threshold for the development of childhood cancer and leukemia at total doses below 1 roentgen is contained in recent studies of prenatal diagnostic x-ray exposure. Implications for the nature of the carcinogenic mechanism in the human organism are discussed, with emphasis on the possible effects of the ionizing radiation from iodine-131 and other short-lived isotopes.