Antibody Production and Development of Contact Skin Sensitivity in Guinea Pigs of Various Ages

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Science  14 Jun 1963:
Vol. 140, Issue 3572, pp. 1211-1212
DOI: 10.1126/science.140.3572.1211


Young adult guinea pigs, 2 months old, showed higher serum antibody titers and greater contact skin sensitivity than those that had reached the average life-span of 2 to 3 years. A transitional response was given by 6-month-old animals.