Complementary RNA in Nucleus and Cytoplasm of Mouse Liver Cells

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Science  28 Jun 1963:
Vol. 140, Issue 3574, pp. 1408-1412
DOI: 10.1126/science.140.3574.1408


The rapidly labeled RNA from both the nuclei and cytoplasm of mouse liver cells can be bound specifically to mouse DNA. The bound fraction differs in base composition and metabolic stability from the bulk RNA. There is considerable cross reaction between this RNA and the DNA obtained from calf thymus.