Thyroxine: Effects on Amino Acid Incorporation into Protein in vivo

See allHide authors and affiliations

Science  28 Jun 1963:
Vol. 140, Issue 3574, pp. 1417-1418
DOI: 10.1126/science.140.3574.1417


Treatment of rats with L-thyroxine increases the incorporation in vivo of radioactive amino acids into protein of liver, kidney, and heart, but not of spleen, testis, or brain. The distribution of the effect among the organs is the same as that observed in thyroxine stimulation of oxidative metabolism. Thus, stimulation of protein synthesis seems to be a physiological action of the thyroid hormone.