"Apocatalase" of Catalase-Negative Staphylococci

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Science  05 Jul 1963:
Vol. 141, Issue 3575, pp. 45-46
DOI: 10.1126/science.141.3575.45


Crystalline catalase of high purity and activity was prepared from a heme-requiring Staphylococcus aureus mutant, JT/52, grown in the presence of heme. A crystalline protein was obtained from the same cells grown without heme. This enzymatically inactive protein and the catalase cross-react strongly when tested by a variety of immunochemical tests.