Synergistic Effect of 5-Bromodeoxyuridine and Gamma Rays on Chromosomes

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Science  19 Jul 1963:
Vol. 141, Issue 3577, pp. 261-262
DOI: 10.1126/science.141.3577.261


The combined effect of 5-bromodeoxyuridine and gamma rays on chromosomes in cells from the root tips of Zebrina pendula is synergistic. The enhanced, combined effects per cell of aberrations, bridges, and acentric fragments were, respectively, 2, 2.4, and 1.9 times the sum of the separate effects.