Renal Tubular Localization of Chlormerodrin Labeled with Mercury-203 by Autoradiography

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Science  02 Aug 1963:
Vol. 141, Issue 3579, pp. 438-440
DOI: 10.1126/science.141.3579.438-a


An autoradiographic technique has been developed for determining the intrarenal distribution of therapeutic doses of chlormerodrin labeled with mercury-203. Highest concentrations of mercury were detected in the straight portion of the proximal tubule in the rat and in the convoluted portion of the proximal tubule in the dog.